Cancer Grand Challenges calls

International teams are now invited to submit an EOI to take on one of these challenges. Awards of up to £20m ($25m) are available and the submission deadline is 18 June. Shortlisted teams will be notified and issued seed funding in July 2025.

• AI-human collaborations in cancer

• Cancer avoidance

• The dark proteome

• Mechanisms driving mutuational signatures

• The nervous system and cancer

• Rewiring cancer cells

• TME dynamics