immunology; gammadelta T cells; hematopoietic stem and precursor cells; early life; fetus


Abstract : γδ T cells are unconventional T cells that express a γδ T cell receptor (TCR) on their cell surface instead of an αβ TCR as on conventional αβ T cells. γδ T cells can have several roles, including protection against infections and tumors. The general approach of our current research is to obtain insight into human γδ T cells by applying sophisticated molecular biological techniques on clinical samples. Important in vivo findings are then further investigated in vitro in order to understand molecular mechanisms. A main focus of our research is the role and ontogeny of human γδ T cells in early life. This research is leading to novel targets (molecules, cells) for pharmacotherapy. A main part of the research is performed at the Institute for Medical Immunology of the ULB.
Promoteur/Supervisor : Prof. Vermijlen David
Email : dvermijl@ulb.ac.be
Site Web/Web site : http://www.ulb.ac.be/facs/pharma/vermijlen.html
Centre de recherche/Research center : DPP; IMI (Institute for Medical Immunology)
Faculté/Faculty : Faculty of Pharmacy/Facult√© de Pharmacie
Ecole doctorale/Graduate Colleges : Biomedical and Pharmaceutical Science/Sciences biomédicales et pharmaceutiques
Ecole doctorale thématique/Graduate School (French Only): Immunologie (EDIM)



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