Leukocyte chemoattractant proteins in angiogenesis and cancer (October 1st 2017)


Abstract : The role of leukocyte chemoattractant molecules (i.e. chemerin) and their receptors in the control of inflammation and tumor progression will be studied. This will involve the use of established and new models of carcinogenesis in mice, receptor and ligand gene inactivation, and conditional expression of chemoattractant molecules in specific cell populations. The aim is to identify and validate G protein-coupled receptors as candidate targets for therapeutic agents in cancer and inflammatory diseases. The Institute of Interdisciplinary Research (IRIBHM, http://www.ulb.ac.be/medecine/iribhm/) is the largest biomedical research department of University of Brussels Medical School (ULB), with state of the art facilities in imaging, molecular and cellular biology and genetics. A strong expertise has been established in the field of G protein-coupled receptors, particularly the functional characterization of novel receptors. A two year grant is available, starting October 1st, 2017 and is renewable.
Promoteur/Supervisor : Prof. Parmentier Marc
Email : mparment@ulb.ac.be
Site Web/Web site : http://www.ulb.ac.be/medecine/iribhm/MP-group/home.html
Centre de recherche/Research center : Institute of Interdisciplinary Research (IRIBHM)
Faculté/Faculty : Faculty of Medicine/Faculté de Médecine
Ecole doctorale/Graduate Colleges : Medical Science/Sciences médicales
Ecole doctorale thématique/Graduate School (French Only): Biologie Cellulaire et Moléculaire, Biochimie (BCMB)



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